Antiviral activity of thiadiazoles, oxadiazoles, triazoles and thiazoles
نویسندگان
چکیده
منابع مشابه
Syntheses, Antibacterial and Antifungal Activities of Substituted-Thiazolo-1,3,4-Thiadiazoles, 1,3,4-Oxadiazoles and 1,2,4-Thiazoles
Starting from readily available 2-substituted-4-methylthiazole-5-carboxylic acid hydrazide (1), The title compounds were prepared. The reaction of compound 1 (R=CH3) with formic acid yielded 1-(formyl)-2-(2,4-dimethylthiazole-5-carboxyl) hydrazine (2). Refluxing the latter with phosphorous pentasulfide in xylene afforded compound 3, the reaction of compound 2 with phosphorous pen...
متن کاملSynthesis of oxadiazoles, thiadiazoles and triazoles derived from benzo[b]thiophene.
In this work 3-chloro-2-chlorocarbonylbenzo[b]thiophene (1) was prepared from cinnamic acid and then converted into the acid hydrazide 2. The azomethines 3a-e were prepared from the corresponding aryl aldehydes and the acid hydrazide 2. Treatment of compound 2 with formic acid gave the N-formyl acid hydrazide 4, which upon refluxing with phosphorous pentoxide or phosphorous pentasulphide in xyl...
متن کاملsyntheses, antibacterial and antifungal activities of substituted-thiazolo-1,3,4-thiadiazoles, 1,3,4-oxadiazoles and 1,2,4-thiazoles
starting from readily available 2-substituted-4-methylthiazole-5-carboxylic acid hydrazide (1), the title compounds were prepared. the reaction of compound 1 (r=ch3) with formic acid yielded 1-(formyl)-2-(2,4-dimethylthiazole-5-carboxyl) hydrazine (2). refluxing the latter with phosphorous pentasulfide in xylene afforded compound 3, the reaction of compound 2 with phosphorous pentoxide afforded...
متن کاملSynthesis and QSAR studies of thiosemicarbazides, 1,2,4-triazoles, 1,3,4- thiadiazoles and 1,3,4-oxadiazoles derivatives as potential antibacterial agents
Several new 2-(2-(4-chlorophenyl)acetyl)-N-arylhydrazinecarbothioamides 1, 5-(4-chlorobenzyl)-4-aryl-4H-1,2,4triazole-3-thiols 2, 5-(4-chlorobenzyl)-N-aryl-1,3,4-thiadiazol-2-amines 3 and 5-(4-chlorobenzyl)-N-aryl-1,3,4-oxadiazol-2amines 4 have been synthesized and screened for their antibacterial activity against gram +ve and gram –ve bacteria i.e S.aureus and E. coli. The QSAR studies of thes...
متن کاملSynthesis and antioxidant activity of a variety of sulfonamidomethane linked 1,3,4-oxadiazoles and thiadiazoles.
A variety of sulfonamidomethane linked 1,3,4-oxadiazoles and 1,3,4-thiadiazoles were prepared and tested for antioxidant activity. The methyl substituted arylsulfonylaminomethyl-1,3,4-oxadiazole 9b showed excellent antioxidant activity.
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2020
ISSN: 1551-7012
DOI: 10.24820/ark.5550190.p011.308